202650 papers
Survival Analysis of the WSG TP-II Trial: Neoadjuvant Trastuzumab and Pertuzumab Plus Endocrine Therapy Versus Chemotherapy in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer.
Gluz O et al. J Clin Oncol. 2026
Clinical and molecular biomarkers for prediction of endocrine response after short preoperative endocrine therapy in the WSG ADAPT-HR+/HER2- and ADAPTcycle trials (N=7914).
Gluz O et al. Ann Oncol. 2026
An Analytical Framework Characterizes the Biological Processes that Shape Copy Number-Based Genome Instability Patterns in Breast Cancer.
Wong H et al. Cancer Res. 2026
TQB2440 compared with reference pertuzumab for HER2-positive, ER/PgR-negative, early or locally advanced breast cancer: a multicenter, randomized, double-blind, parallel-controlled, phase III equivalence trial.
Wang S et al. ESMO Open. 2026
VIKTORIA-1 Trial of Gedatolisib Plus Fulvestrant With or Without Palbociclib in Hormone Receptor-Positive/HER2-/PIK3CA Wild-Type Advanced Breast Cancer.
Hurvitz SA et al. J Clin Oncol. 2026
Molecular profile of residual triple-negative breast cancer: opportunities for post-neoadjuvant therapeutic interventions.
van den Ende NS et al. NPJ Breast Cancer. 2026
A phase IV prospective study of efficacy and safety of ribociclib and letrozole as first-line therapy in older women (≥70 years) with hormone receptor-positive HER2-negative advanced breast cancer: the RibOB study.
Van Houdt M et al. ESMO Open. 2026
Extended Endocrine Therapy Following 5 Years of Adjuvant Luteinizing Hormone-Releasing Hormone Agonist in Premenopausal Patients With Node-Positive, Hormone Receptor-Positive Breast Cancer: A Cohort Study.
Valenza C et al. J Clin Oncol. 2026
Analysis of UGT1A1 germline variants in patients with advanced breast cancer treated with trastuzumab-deruxtecan: results from the PROCURE Project.
Sánchez-Bayona R et al. ESMO Open. 2026
Datopotamab deruxtecan in patients with untreated, advanced triple-negative breast cancer (TROPION-Breast02): a randomised, open-label, international, phase III trial.
Dent R et al. Ann Oncol. 2026
TRADE: a phase II trial to assess the tolerability of abemaciclib dose escalation in early-stage HR-positive/HER2-negative breast cancer.
Mayer EL et al. Ann Oncol. 2026
Preclinical characterization and phase 1 results of TQB2102, a first-in-class HER2 biparatopic antibody-drug conjugate, in patients with advanced solid tumors.
Ruan DY et al. Ann Oncol. 2026
Sacituzumab Govitecan plus Pembrolizumab for Advanced Triple-Negative Breast Cancer.
Tolaney SM et al. N Engl J Med. 2026
Molecular imaging of tucatinib-induced cellular and TME changes in preclinical models of HER2 + breast cancer.
Song PN et al. Breast Cancer Res Treat. 2026
TLR7 signature of tumour innervation reveals two distinct pathways of triple-negative breast cancer progression.
Wang DY et al. Br J Cancer. 2026
TBCRC 048 (Olaparib Expanded) Expansion Cohorts: Phase II Study of Olaparib Monotherapy for Patients With Metastatic Breast Cancer With Germline Mutations in PALB2 or Somatic Mutations in BRCA1 or BRCA2.
Tung NM et al. J Clin Oncol. 2026
TBCRC 035: randomized phase II pharmacodynamic study of standard and reduced-dose palbociclib with endocrine therapy in hormone receptor (HR)-positive previously treated metastatic breast cancer.
Jacob S et al. ESMO Open. 2026
Adjuvant capecitabine in women with triple-negative breast cancer with residual disease after carboplatin-containing neoadjuvant chemotherapy.
Tavares GM et al. Breast Cancer Res Treat. 2026
Single-cell transcriptomics reveals immune landscape dynamics in metastatic hormone receptor-positive breast cancer treated with abemaciclib and endocrine therapy.
Strawser CH et al. Clin Cancer Res. 2026
Change in practice patterns over time for endocrine therapy and radiation therapy in women with breast cancer age 65 and older.
Stickland A et al. Breast Cancer Res Treat. 2026
Impact of immune-related adverse events on response to neoadjuvant chemoimmunotherapy in triple-negative breast cancer: a single-institution retrospective study.
Sterpi M et al. Breast Cancer Res Treat. 2026
Real-world outcomes of reduced-dose versus standard-dose antibody drug conjugates in metastatic breast cancer: a retrospective cohort study.
Stabellini N et al. Breast Cancer Res Treat. 2026
Neoadjuvant therapy with an aromatase inhibitor and durvalumab in postmenopausal patients with hormone receptor-positive breast cancer.
Soyano Muller AE et al. Breast Cancer Res Treat. 2026
Genomic Determinants of Response to Alpelisib Plus Fulvestrant in the SOLAR-1 Trial.
Juric D et al. Ann Oncol. 2026
Final outcomes of the SOFT and TEXT phase III trials in premenopausal hormone receptor-positive early breast cancer.
Francis PA et al. Ann Oncol. 2026
Combination of predicted sensitivity to endocrine therapy (SET2,3 index) and the recurrence score® in node-positive breast cancer: Independent validation in the PACS-01 trial.
Penault-Llorca F et al. Eur J Cancer. 2026
Pharmacodynamics of Camizestrant Treatment in Postmenopausal Women With Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Primary Breast Cancer: Results From the Randomized, Presurgical SERENA-3 Study.
Robertson JFR et al. J Clin Oncol. 2026
The SDC1-ENO1 Axis in Cancer-Associated Fibroblasts Generates a Lactate-Rich Microenvironment That Drives Tumor Radioresistance.
Hou X et al. Cancer Res. 2026
Durvalumab Plus Paclitaxel, with or without Capivasertib or Oleclumab, in Patients with Locally Advanced/Metastatic Triple-Negative Breast Cancer.
Schmid P et al. Clin Cancer Res. 2026
Sacituzumab govitecan in patients with metastatic breast cancer: pooled safety analysis of data from patients in North America, Europe, and Asia.
Rugo HS et al. ESMO Open. 2026
Emerging Strategies to Inhibit the G1/S Transition for Cancer Therapy.
Rubin SM et al. Cancer Res. 2026
Adjuvant Epirubicin Plus Cyclophosphamide Followed by Taxanes With or Without Carboplatin in Early-Stage Triple-Negative Breast Cancer (RJBC 1501): A Randomized Phase III Trial.
Chen X et al. J Clin Oncol. 2026
Long-term outcomes in triple-negative breast cancer after a pathologic complete response: does the type of neoadjuvant therapy matter?
Ravani LV et al. Breast Cancer Res Treat. 2026
Exploratory analysis of PTEN deficiency by immunohistochemistry from the Phase III CAPItello-291 trial.
Jhaveri K et al. Clin Cancer Res. 2026
Updated Results of the POSITIVE (Pregnancy Outcome and Safety of Interrupting Therapy for Women with Endocrine Responsive Breast Cancer) Trial.
Pagani O et al. Ann Oncol. 2026
Expert recommendations for PIK3CA testing in HR+/HER2- locally advanced and metastatic breast cancer.
Marchiò C et al. NPJ Breast Cancer. 2026
Alpelisib and Fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the German PRAEGNANT trial.
Hörner M et al. Breast Cancer Res Treat. 2026
PIK3CA mutations and first-line outcomes in endocrine-resistant HR+/HER2- metastatic breast cancer: A multicentric real-world study.
Dieci MV et al. Eur J Cancer. 2026
PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical Models.
Juric D et al. Clin Cancer Res. 2026
PI3K Inhibition in Combination with Tamoxifen in Patients with Metastatic HR+/HER2- Breast Cancer: Clinical and Circulating Tumor DNA Results.
Voorthuis RAB et al. Clin Cancer Res. 2026
Tucatinib Gives PFS Boost for Metastatic Breast Cancer.
Cancer Discov. 2026
Potency and safety of novel [225Ac]Ac-labeled pertuzumab-PEGylated emtansine drug conjugate against HER2-positive breast cancer.
Pougoue Ketchemen J et al. Br J Cancer. 2026
Clinical Validation of Digital PCR-Based ctDNA Detection for Risk Stratification in Residual Triple-Negative Breast Cancer: TRICIA Trial Results.
Roseshter T et al. Clin Cancer Res. 2026
PATINA — Palbociclib + Anti-HER2 Therapy + ET in HR+/HER2+ MBC
Metzger O et al. NEJM. 2026
PARP inhibition with olaparib and talazoparib for HER2-negative advanced breast cancer-Results from the prospective PRAEGNANT registry.
Hörner M et al. NPJ Breast Cancer. 2026
Simultaneous inhibition of PARP/AKT to intercept nascent BRCA1/2mut breast tumors.
Wang L et al. NPJ Breast Cancer. 2026
Clonal Hematopoiesis and Risk of Trastuzumab-Related Cardiotoxic Effects.
Park CS et al. JAMA Oncol. 2026
OPTIMAL: A Multinational Phase III Study of Oral Paclitaxel (DHP107) versus Intravenous Weekly Paclitaxel in HER2-Negative Recurrent or Metastatic Breast Cancer.
Xu B et al. Ann Oncol. 2026
OPERA: a phase II study of DHP107 (oral paclitaxel) versus intravenous paclitaxel in patients with HER2-negative recurrent or metastatic breast cancer.
Rugo HS et al. Breast Cancer Res Treat. 2026
Comparison of suboptimal versus adequate ovarian function suppression in premenopausal women with early breast cancer treated with adjuvant endocrine therapy: An exploratory analysis of two prospective studies.
Nardin S et al. Eur J Cancer. 2026