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Ewing SarcomaAdvanced/Metastatic2026

Phase I/II Study of the PARP Inhibitor Olaparib and Irinotecan in Children and Young Adults with Recurrent/Refractory Malignancies: Arm D of the AcSé-ESMART Trial.

Gatz SA et al. Clin Cancer Res. 2026

Ewing SarcomaAll Stages2026

Multicenter Histology Image Integration and Multiscale Deep Learning Support Machine Learning-Enabled Pediatric Sarcoma Classification.

Thiesen AH et al. Cancer Res. 2026

Soft Tissue SarcomaAdvanced/Metastatic2026

Trabectedin-olaparib combination or trabectedin in advanced soft tissue sarcomas after failure of anthracycline-based treatment (TOMAS2): a randomized phase II study from the Italian Sarcoma Group.

D'Ambrosio L et al. Ann Oncol. 2026

Ewing SarcomaAll Stages2026

Validation of a Seven-Gene Predictive SIGNature for the Efficacy of Immuno-Oncology PD-1 Inhibitors in Patients with Sarcoma.

Moura DS et al. Clin Cancer Res. 2026

LiposarcomaAll Stages2026

Overall survival from the open-label phase II trial of palbociclib in patients with advanced well-differentiated/dedifferentiated liposarcoma.

Babatunde OO et al. ESMO Open. 2026

Ewing SarcomaAll Stages2026

Addition of zoledronic acid to consolidation chemotherapy in Ewing sarcoma-EURO EWING 2012 (EE2012): an international, open-label, randomised controlled phase III trial.

Bernadette B et al. Br J Cancer. 2026

Ewing SarcomaAll Stages2026

FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy.

Gracilla DE et al. Cancer Res. 2026

LiposarcomaAll Stages2026

Targeting the Non-Homologous End-Joining Pathway Sensitizes MDM2-Amplified Liposarcoma to Doxorubicin by Enhancing p53-Mediated Senescence.

Jalving T et al. Cancer Res. 2026

Soft Tissue SarcomaAll Stages2026

Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.

Baldi GG et al. Eur J Cancer. 2026

Soft Tissue SarcomaAll Stages2026

Activity of chemotherapy in mesenchymal chondrosarcoma: a multicentre retrospective analysis within the Italian Sarcoma Group network.

Baldi GG et al. ESMO Open. 2026

Soft Tissue SarcomaAdvanced/Metastatic2026

First-line Anlotinib plus Anthracyclines and Ifosfamide Followed by Anlotinib Maintenance in Advanced Soft-Tissue Sarcoma: A Phase II Single-Arm Trial.

Zhao JK et al. Clin Cancer Res. 2026

LiposarcomaAll Stages2026

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single-Arm Meta-Analysis.

Delgado LM et al. J Surg Oncol. 2026

OsteosarcomaAll Stages2026

Spermidine Secreted by Apoptotic Cells Enhances Chemotherapy Resistance by Modulating β-Catenin Activity in Osteosarcoma.

Yu Q et al. Clin Cancer Res. 2026

GISTAdvanced/Metastatic2026

Cancer-Associated Fibroblasts Promote Imatinib Resistance in Gastrointestinal Stromal Tumors through PGK1-Mediated Metabolic Reprogramming.

Li C et al. Cancer Res. 2026

Soft Tissue SarcomaAdvanced/Metastatic2026

Phase IB/II Trial with Correlative Analyses of Doxorubicin plus Durvalumab Combination in Patients with Advanced Soft Tissue Sarcoma.

Yun KH et al. Clin Cancer Res. 2026

Ewing SarcomaAdvanced/Metastatic2026

Interest of a sequential multimodal approach for the treatment of newly diagnosed patients with multimetastatic Ewing sarcoma: results of the French prospective CombinaiR3 phase II trial.

Laurence V et al. Br J Cancer. 2026

Soft Tissue SarcomaAdvanced/Metastatic2026

Clinical, immunological, and genomic findings of atezolizumab in advanced alveolar soft part sarcoma: A phase II trial (ALBERT trial/NCCH1907).

Kojima Y et al. Eur J Cancer. 2026

LiposarcomaAll Stages2026

Pancreaticoduodenectomy and IVC resection in retroperitoneal sarcoma: Expanding the limits of feasible surgery.

Benuzzi L et al. Eur J Surg Oncol. 2026

LiposarcomaAll Stages2025

The Impact of Perioperative Radiotherapy on Disease-Specific Survival in Patients with Localized Retroperitoneal Liposarcoma: A Population-Based Propensity-Score Matched Analysis.

Wilhelm A et al. Ann Surg Oncol. 2025

LiposarcomaAll Stages2025

Neoadjuvant Immunotherapy for Resectable Dedifferentiated Liposarcoma: A National Cohort Analysis.

Farooq MS et al. J Surg Oncol. 2025

Liposarcomaearly2025

Sarcoma: Last Year's Practice Changing Papers.

van Houdt WJ et al. Ann Surg Oncol. 2025

Liposarcomaearly2025

Radiologic and Pathologic Response Evaluation After Neoadjuvant Chemotherapy for Primary Retroperitoneal Sarcoma: A Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) Collaboration.

van der Burg SJC et al. Ann Surg Oncol. 2025

Liposarcomaearly2025

ASO Practice Guidelines Series: Soft Tissue Sarcoma of the Extremities and Superficial Trunk.

Callegaro D et al. Ann Surg Oncol. 2025

LiposarcomaAll Stages2025

Six Surgical Stages in the Resection of Primary Left Retroperitoneal Liposarcoma: A Standardized Comprehensive Approach.

Baia M et al. Ann Surg Oncol. 2025

Liposarcomaearly2025

Incomplete Cancer Surgery Correlates With Loss of Immune Surveillance and Hyper-Progression of Disease.

Fine SA et al. J Surg Oncol. 2025

Liposarcomaearly2025

Temporospatial Recurrence Patterns and Predictive Factors for Recurrences in 984 Patients With Adult Soft Tissue Sarcomas.

Deo S et al. J Surg Oncol. 2025

LiposarcomaAdvanced/Metastatic2025

A phase I dose-escalation and dose-expansion study of tibremciclib, a novel CDK4/6 inhibitor, monotherapy and in combination with fulvestrant in HR-positive/HER2-negative advanced breast cancer.

Zhang J et al. ESMO Open. 2025

LiposarcomaAll Stages2025

Assessing targetable NTRK1/2/3 fusions in mesenchymal tumors via whole-exome RNA sequencing.

Vanacker H et al. ESMO Open. 2025

LiposarcomaAdvanced/Metastatic2025

Letetresgene Autoleucel in Advanced/Metastatic Myxoid/Round Cell Liposarcoma.

D'Angelo SP et al. J Clin Oncol. 2025

LiposarcomaAdvanced/Metastatic2025

The role of whole-genome sequencing for guiding systemic therapy in patients with soft tissue sarcoma.

van der Laan P et al. ESMO Open. 2025

LiposarcomaAll Stages2025

Characterizing the Transformation and Diagnosis of Atypical Lipomatous Tumor to Dedifferentiated Liposarcoma: Single Institutional Outcomes.

Butler Z et al. J Surg Oncol. 2025

LiposarcomaAdvanced/Metastatic2025

An onco-vascular surgical approach: Internal iliac artery transposition for external iliac artery repair during cytoreductive surgery.

Altınsoy E et al. Eur J Surg Oncol. 2025

Soft Tissue Sarcomaearly2025

Redefining radiologic responses in high-risk soft-tissue sarcomas treated with neoadjuvant chemotherapy: final results of ISG-STS 1001, a randomized clinical trial.

Vanzulli A et al. ESMO Open. 2025

LiposarcomaAdvanced/Metastatic2025

Immunocompetent Murine Models Recapitulate the Heterogeneous Tumor-Immune Microenvironment of Human Liposarcoma.

Shafer AM et al. Clin Cancer Res. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

Regorafenib as maintenance therapy after first-line doxorubicin-based chemotherapy in advanced non-adipocytic soft tissue sarcomas patients: a double-blind randomised trial.

Penel N et al. Ann Oncol. 2025

GISTAdvanced/Metastatic2025

Imatinib alternating with regorafenib compared to imatinib alone for the first-line treatment of advanced gastrointestinal stromal tumor: The AGITG ALT-GIST intergroup randomized phase II trial.

Yip D et al. Br J Cancer. 2025

GISTearly2025

Clinical description and development of a prognostic score for neurofibromatosis type 1 (NF1)-associated GISTs: a retrospective study from the NETSARC.

Cuvelier C et al. ESMO Open. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

A Single-Arm Phase 2 Trial of Doxorubicin Plus Zalifrelimab (Anti-CTLA-4 Antibody) and Balstilimab (Anti-PD-1 Antibody) in Advanced/Metastatic Soft Tissue Sarcomas.

Wilky BA et al. Clin Cancer Res. 2025

LiposarcomaAll Stages2025

Cumulative incidence and survival outcomes of brain metastases in sarcoma: a large single center retrospective analysis.

Erjan A et al. Br J Cancer. 2025

GISTearly2025

A Systematic Review with a Demonstrative Case of KIT and DOG-1 Expressing Gastrointestinal Stromal Tumors Harboring ETV6-NTRK3 Fusions.

Ranjbarian T et al. Clin Cancer Res. 2025

GISTAdvanced/Metastatic2025

AT101 Suppresses Gastrointestinal Stromal Tumor Growth and Promotes Apoptosis via YAP/TAZ-CCND1 and FBXW7-MCL1 Axes.

Wu X et al. Ann Surg Oncol. 2025

GISTAll Stages2025

Intratumoral Bacteria are Uncommon in Gastrointestinal Stromal Tumor.

Tardy KJ et al. Ann Surg Oncol. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

A Phase II Multicenter Trial of Trabectedin in Combination with Olaparib in Patients with Advanced Unresectable or Metastatic Sarcoma.

Siontis BL et al. Clin Cancer Res. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

Ribociclib in Sequential Combination with Doxorubicin in Anthracycline-Naïve Advanced Soft-Tissue Sarcomas: Results of a Dose-Finding Phase Ib Study.

Davis LE et al. Clin Cancer Res. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

Ossifying fibromyxoid tumours: A case series.

Pozas J et al. Eur J Cancer. 2025

Soft Tissue SarcomaAdvanced/Metastatic2025

Efficacy, safety, and pharmacokinetics of eribulin as monotherapy or in combination with irinotecan for patients with pediatric rhabdomyosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, or Ewing sarcoma.

Casanova M et al. ESMO Open. 2025

LiposarcomaAll Stages2025

Evaluation of Diagnostic Accuracy of Preoperative CT-Based Radiomics in Primary Retroperitoneal Sarcoma.

Tirotta F et al. Ann Surg Oncol. 2025

LiposarcomaAll Stages2025

Characterizing Socioeconomic Factors That Influence Treatment Selection in Myxoid Liposarcoma: A Population-Based Study From the Surveillance, Epidemiology, and End Results Database.

Joachim K et al. J Surg Oncol. 2025

LiposarcomaAll Stages2025

Combined Laparoscopic and Open Surgical Approach for Well Differentiated Trans-compartmental Liposarcoma Between Pelvic and Femoral Regions.

Aulicino M et al. Ann Surg Oncol. 2025

GISTAdvanced/Metastatic2025

Updated Overall Survival and Long-Term Safety With Ripretinib Versus Sunitinib in Patients With GI Stromal Tumor: Final Overall Survival Analysis From INTRIGUE.

Heinrich MC et al. J Clin Oncol. 2025