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202650 papers

Tumor MicroenvironmentAll Research2026

ZO-1 shuttles between apical junctional complexes and podosomes by riding ERK activation waves.

Hirano S et al. Nat Commun. 2026

Signaling PathwaysAll Research2026

M6A-dependent upregulation of ZNF460 promotes epithelial-mesenchymal transition and metastasis of gastric cancer through a histone modification-mediated positive feedback loop.

Yue B et al. Oncogene. 2026

EpigeneticsAll Research2026

ZNF296 Drives Immune Evasion in Epithelial Cancers by Repressing Immune Stimulatory Genes.

Wang H et al. Cancer Res. 2026

EpigeneticsAll Research2026

ZNF274 constrains lineage plasticity and drives intrinsic resistance to CDK7 inhibitors in pancreatic cancer.

Gianopulos JE et al. Nat Commun. 2026

Oncogenes & Tumor SuppressorsAll Research2026

A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma.

Zhuo M et al. Cancer Cell. 2026

Cancer Stem CellsAll Research2026

Stem cells as an essential mediator of the exercise-tumorigenesis link.

Zhuang X et al. Nat Rev Cancer. 2026

EpigeneticsAll Research2026

microRNA-25 drives immune checkpoint therapy resistance by repressing innate and humoral immunity via Syndecan-3.

Zhu Z et al. Nat Commun. 2026

Cell DeathAll Research2026

Apoptosis-inducing factor starts its activity within mitochondria revealed by in situ vibrational probes.

Zhu J et al. Proc Natl Acad Sci U S A. 2026

Oncogenes & Tumor SuppressorsAll Research2026

Activating p53Y220C with a mutant-specific small molecule.

Zhu X et al. Nat Commun. 2026

Cancer MetabolismAll Research2026

Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer.

Zhu L et al. Mol Cell. 2026

Signaling PathwaysAll Research2026

Testosterone and cancers: biological functions, molecular mechanisms and therapy.

Zhou Z et al. Mol Cancer. 2026

Tumor ImmunologyAll Research2026

Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression.

Zhou YD et al. Cell Rep. 2026

Signaling Pathwaysadvanced2026

Targeting inflammatory microenvironments: overcoming therapy resistance and immunosuppression.

Zhou Y et al. Mol Cancer. 2026

Signaling PathwaysAll Research2026

Cancer stem cell-driven drug resistance in colorectal carcinoma: molecular aspects and therapeutic potentials.

Zhou M et al. Mol Cancer. 2026

MetastasisAll Research2026

Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.

Zhou Y et al. Nat Commun. 2026

Cancer MetabolismAll Research2026

Metabolic characteristics in hepatocellular carcinoma: amino acid metabolic reprogramming.

Zhou R et al. Mol Cancer. 2026

Signaling Pathwaysadvanced2026

Extracellular Vesicle-Packaged miR-99a Reprograms Fibroblasts to Create an Inflammatory Niche That Drives Colorectal Cancer Metastasis.

Zhou M et al. Cancer Res. 2026

MetastasisAll Research2026

Q&A with Hua Zhong.

Zhong H et al. Cell Rep. 2026

Tumor MicroenvironmentAll Research2026

Targeting mitochondrial homeostasis as a cancer treatment strategy: current status and future prospects.

Zhong H et al. Mol Cancer. 2026

Tumor MicroenvironmentAll Research2026

Interpretable, flexible and spatially aware integration of multiple spatial transcriptomics datasets from diverse sources.

Zhao J et al. Nat Genet. 2026

Tumor Microenvironmentearly2026

Neoadjuvant toripalimab plus CapeOX in locally advanced Epstein-Barr virus-associated gastric or gastroesophageal junction adenocarcinoma: a phase Ⅱ trial.

Zhao L et al. Nat Commun. 2026

Tumor Microenvironmentearly2026

Dissecting genetic and immune drivers of heterogeneous responses to neoadjuvant immunochemotherapy in gastric cancer.

Zhao Q et al. Cancer Cell. 2026

Metastasisadvanced2026

Insight of immune checkpoint blockades in melanoma: mechanism and clinical translation.

Zhang Q et al. Mol Cancer. 2026

Metastasisadvanced2026

Ki-67 promotes circulating tumor cell intravasation and metastasis in breast cancer.

Zhang Y et al. Cell Rep. 2026

Cancer Stem CellsAll Research2026

Tumors mimic the niche to inhibit neighboring stem cell differentiation.

Zhang Y et al. Elife. 2026

EpigeneticsAll Research2026

Non-invasive profiling of the tumour microenvironment with spatial ecotypes.

Zhang W et al. Nature. 2026

Cancer MetabolismAll Research2026

Cancer cachexia: A tumor-driven disorder of whole-body homeostasis.

Zhang Y et al. Cancer Cell. 2026

Tumor ImmunologyAll Research2026

Molecular insights into early malignant transition of hepatocellular carcinoma.

Zhang Z et al. Cancer Cell. 2026

Tumor MicroenvironmentAll Research2026

Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment.

Zhang SW et al. Cell. 2026

Signaling PathwaysAll Research2026

Covalent modification of a glutamic acid inspired by HaloTag technology.

Zhang R et al. Nat Commun. 2026

Cell DeathAll Research2026

Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function.

Zhang B et al. Elife. 2026

MetastasisAll Research2026

Genomic evolution of pancreatic cancer at single-cell resolution.

Zhang H et al. Nat Genet. 2026

EpigeneticsAll Research2026

Lactate: elucidating its indispensable role in human health.

Zhang S et al. Mol Cancer. 2026

Tumor ImmunologyAll Research2026

Innate immunity in tumour immunoediting and immunosurveillance.

Zhang Z et al. EMBO J. 2026

Signaling PathwaysAll Research2026

ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression.

Natarajan SK et al. Nature. 2026

Tumor MicroenvironmentAll Research2026

Mechanisms of tumor-derived extracellular vesicle-mediated immunometabolic reprogramming and immunotherapeutic resistance.

Zeng H et al. Mol Cancer. 2026

Tumor MicroenvironmentAll Research2026

Multiscale imaging on proton pump-driven acidity for assessing tumor progression and metastasis.

Zeng S et al. Nat Commun. 2026

DNA RepairAll Research2026

Targeting ZDHHC12-mediated PARP1 palmitoylation potentiates PARP inhibitor cytotoxicity.

Zhang X et al. Cell Rep. 2026

Metastasisadvanced2026

ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation.

Monteagudo-García Ó et al. Cancer Res. 2026

Oncogenes & Tumor SuppressorsAll Research2026

Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia.

Arnuk A et al. Sci Transl Med. 2026

Tumor MicroenvironmentAll Research2026

Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.

Zarodniuk M et al. Proc Natl Acad Sci U S A. 2026

Cancer Metabolismadvanced2026

Drink Responsibly: Cancer Cells Also Like Sugary Drinks.

Zani F et al. Cancer Res. 2026

Cell DeathAll Research2026

Damage-induced i-loops generate eccDNA from repetitive elements.

Zanella E et al. Mol Cell. 2026

Metastasisadvanced2026

Aneuploidy patterns in colorectal cancer.

Zaalberg IC et al. Cell Rep. 2026

Cancer Stem CellsAll Research2026

The YY1-KIF15-PRDX1 axis promotes gastric cancer progression by inducing mitochondrial ROS imbalance.

Li W et al. Oncogene. 2026

MetastasisAll Research2026

Rethinking immune states in brain metastasis.

Yuan X et al. Cancer Cell. 2026

Tumor MicroenvironmentAll Research2026

A Spatial Atlas of Muscle-Invasive Bladder Cancer Reveals Lineage-Specific Vulnerabilities and Immune Architecture.

Yu K et al. Cancer Discov. 2026

Cancer Stem CellsAll Research2026

Genome-wide sweeps create ecological units in the human gut microbiome.

Yu XA et al. Nature. 2026

Signaling PathwaysAll Research2026

Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.

Yu H et al. Mol Cancer. 2026

Tumor Immunologyearly2026

An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice.

Yu H et al. Nat Commun. 2026